{"id":277,"date":"2020-09-04T19:29:31","date_gmt":"2020-09-04T19:29:31","guid":{"rendered":"https:\/\/www.hospitalinnovate.org\/covid19\/?p=277"},"modified":"2020-09-21T23:30:23","modified_gmt":"2020-09-21T23:30:23","slug":"11what-is-the-optimal-vte-treatment-strategy-dosing-route-of-administration-frequency-duration","status":"publish","type":"post","link":"https:\/\/www.hospitalinnovate.org\/covid19\/2020\/09\/04\/11what-is-the-optimal-vte-treatment-strategy-dosing-route-of-administration-frequency-duration\/","title":{"rendered":"11. What is the optimal VTE treatment strategy (dosing, route of administration, frequency, duration)?"},"content":{"rendered":"<p>[vc_row full_width=&#8221;stretch_row_content_no_spaces&#8221; css=&#8221;.vc_custom_1599595995354{margin-top: 0px !important;border-bottom-width: 4px !important;padding-top: 0px !important;padding-right: 20px !important;padding-bottom: 0px !important;padding-left: 20px !important;background-color: #f2f2f2 !important;border-bottom-color: #2c5d73 !important;border-bottom-style: solid !important;}&#8221;][vc_column width=&#8221;2\/3&#8243; css=&#8221;.vc_custom_1599247143020{padding-right: 20px !important;padding-left: 10px !important;}&#8221;][vc_custom_heading text=&#8221;Prevention and Treatment of Venous Thromboembolism Key Clinical Questions&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23f7941d&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;.vc_custom_1599247161415{margin-top: 0px !important;padding-top: 40px !important;}&#8221;][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_column_text]<\/p>\n<p style=\"text-align: right;\"><a href=\"https:\/\/www.hospitalinnovate.org\/covid19\/\">Home<\/a> \/ <a href=\"https:\/\/www.hospitalinnovate.org\/covid19\/vte-overview\/\">VTE Overview<\/a> \/ <a href=\"https:\/\/www.hospitalinnovate.org\/covid19\/category\/vte\/\">VTE Clinical Questions<\/a><\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row_content_no_spaces&#8221; gap=&#8221;20&#8243;][vc_column width=&#8221;3\/4&#8243; css=&#8221;.vc_custom_1599596059091{padding: 20px !important;}&#8221;][vc_custom_heading source=&#8221;post_title&#8221; use_theme_fonts=&#8221;yes&#8221;][vc_column_text]<\/p>\n<h3><strong>a. HOMERuN institutions<\/strong><\/h3>\n<p>Fifteen protocols (71%) addressed this question. In those that addressed the type of anticoagulant used and the duration, all were consistent with the standard recommendations for treating VTE in patients without COVID-19, i.e., LMWH, DOAC, or warfarin for at least 3 months including standard caveats for renal function, weight, mechanical heart valves, or LVADs.[\/vc_column_text][vc_row_inner gap=&#8221;30&#8243; css=&#8221;.vc_custom_1599596074851{padding: 20px !important;}&#8221;][vc_column_inner width=&#8221;1\/2&#8243;][vc_column_text]<\/p>\n<h3><strong>b. What is Known<\/strong><\/h3>\n<p>Information on this question has all been extrapolated from preexisting data in non-COVID patients.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_column_text]<\/p>\n<h3><strong>c. What is Not Known<\/strong><\/h3>\n<p>There is currently no direct evidence to inform the optimal VTE treatment strategy in COVID-19 patients specifically, though randomized clinical trials are ongoing.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=&#8221;1\/4&#8243; css=&#8221;.vc_custom_1600127179517{border-top-width: 1px !important;border-right-width: 1px !important;border-bottom-width: 1px !important;border-left-width: 4px !important;padding-top: 20px !important;padding-right: 20px !important;padding-bottom: 20px !important;padding-left: 20px !important;border-left-color: #2c5d73 !important;border-left-style: solid !important;border-right-color: #2c5d73 !important;border-right-style: solid !important;border-top-color: #2c5d73 !important;border-top-style: solid !important;border-bottom-color: #2c5d73 !important;border-bottom-style: solid !important;border-radius: 4px !important;}&#8221;][vc_raw_html]JTVCdWx0aW1hdGVfcG9zdF9saXN0JTIwaWQlM0QlMjIxMjQlMjIlNUQ=[\/vc_raw_html][vc_wp_custommenu nav_menu=&#8221;3&#8243; title=&#8221;VTE Links&#8221; el_class=&#8221;subNavButton&#8221;][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nineteen percent of protocols recommended standard pharmacologic VTE prophylaxis dosing for all COVID-19 patients regardless of estimated VTE risk. Ten percent recommended&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"_links":{"self":[{"href":"https:\/\/www.hospitalinnovate.org\/covid19\/wp-json\/wp\/v2\/posts\/277"}],"collection":[{"href":"https:\/\/www.hospitalinnovate.org\/covid19\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hospitalinnovate.org\/covid19\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hospitalinnovate.org\/covid19\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hospitalinnovate.org\/covid19\/wp-json\/wp\/v2\/comments?post=277"}],"version-history":[{"count":6,"href":"https:\/\/www.hospitalinnovate.org\/covid19\/wp-json\/wp\/v2\/posts\/277\/revisions"}],"predecessor-version":[{"id":636,"href":"https:\/\/www.hospitalinnovate.org\/covid19\/wp-json\/wp\/v2\/posts\/277\/revisions\/636"}],"wp:attachment":[{"href":"https:\/\/www.hospitalinnovate.org\/covid19\/wp-json\/wp\/v2\/media?parent=277"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hospitalinnovate.org\/covid19\/wp-json\/wp\/v2\/categories?post=277"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hospitalinnovate.org\/covid19\/wp-json\/wp\/v2\/tags?post=277"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}